Is This Entity Related to Posterior Reversible Leukoencephalopathy?
We read with interest Saigal et al s (1) article, MR Findings of Cortical Blindness Following Cerebral Angiography, in the February 2004 issue of the AJNR. The authors reported MR imaging findings in three cases of cortical blindness following cerebral angiography in which nonionic contrast media were used. These cases exhibited clinical and radiological findings that were relatively similar to those associated with posterior reversible leukoencephalopathy (PRLE), which suggests a common pathophysiology. On the basis of their experience, Saigal et al have hypothesized that the pathophysiological mechanisms of cortical blindness following cerebral angiography and PRLE may be related. Posterior reversible encephalopathy syndrome, hypertensive encephalopathy, reversible posterior cerebral edema syndrome, and PRLE are all terms that have been used to describe a group of disorders that present clinically with headache, seizures, visual changes, altered mental status, and occasionally, focal
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