I have checked with local pet shops and aquarium sites, but not having much luck here. I have following setup: -55 gal freshwater tank -tap water is hard water that I’m told is treated with chlorine gas and polyphosphate to keep iron in suspension -I have a water softener that uses salt for re-charging -I make water changes direct from tap using python gravel vacuum. – The replacement water comes right from the tap, and is mix of softened water (hot tap) and hard untreated water (cold tap) to balance temperature. -I then add some aquarium fresh water salt treatment -I add sodium thiosulfate for chlorine neutralizer While I’ve done this water change process for years without issues, recently there has been some type of chemical reaction that has been very hard on my fish. Problem appears as a gradual clouding of the water after partial water change – getting really bad in about 3 hours. At this point the fish are at the surface gasping for air.