Is there much difference between the brand Coumadin and generic warfarin?
There have been a few published reports of people having this INR increase or decrease when they were switched from one to the other. However, there have been no published studies the showed any significant difference. I have not seen anyone who had any serious problem from making the switch. For a good review of this, copy the line below and paste it into your browser’s address section. http://www.medscape.com/SMA/SMJ/2001/v94.n01/smj9401.03.hend/smj9401.03.hend-05.