Is there information about the use of Caninsulin in rabbits?
Caninsulin is not registered for use in rabbits. The following information is provided by Dr. Thomas Göbel (Kleintierpraxis, Mecklenburgische Straße 27 14197 Berlin.) Background Information Diabetes mellitus in rabbits resembles insulin-independent diabetes in humans. Whether insulin secretion is limited, maintained or elevated, tissue sensitivity to insulin is decreased (peripheral insulin resistance), resulting in a relative insulin deficit. The characteristic clinical signs are polydipsia, polyuria as well as polyphagia and weight loss. Occasionally, uni- or bilateral cataracts are observed. There is also glucosuria. The diagnosis is made based on the history, clinical signs and blood sugar concentrations measuring repeatedly above 300 mg/dl (16.7 mmol/l). Dosage The dosage of Caninsulin that is administered to a diabetic rabbit should be based on the level of control of blood glucose concentrations. An initial dose of 1 unit per kg once daily is recommended. On the basis of the eff