Is there help for the heart defects associated with Trisomy 18?
Review of the literature notes there are several possible birth heart defect that can be associated with Trisomy 18. The most common include ventricular septal defect, atrial septal defect, and pulmonary stenosis. Other reported defects include bicuspid aortic valve and more complex lesions such as double outlet right ventricle. These children can also have a persisting normal patent ductus arteriosus that may contribute to symptoms such as increased work of breathing or feeding. They may also have persistent increased pulmonary vascular resistance, often referred to as pulmonary hypertension. Consider reviewing www.pted.org as an excellent website for general reviews of specific heart defects. Trisomy 18 is often considered a lethal genetic disorder with poor long-term prognosis and often death early in the first year of life. The more severe the heart disease, the more likely the child will die from cardiopulmonary disease. The children are also at greater risk for neurological disor
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