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Is there evidence to substantiate the use Glivec as first-line treatment in CML?

April 26, 2017CML first-line glivec substantiate treatment

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Is there evidence to substantiate the use Glivec as first-line treatment in CML?

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• Yes. The large phase 3 randomised IRIS trial has demonstrated superior efficacy of Glivec over IFN-α + Ara-C, the previous standard of care for patients with newly diagnosed chronic-phase CML. Large phase 2 studies have demonstrated efficacy of Glivec in more advanced phases of CML4.