Is There Evidence That EDTA Chelation Therapy Reverses Coronary Artery Disease (CAD)?
The bulk of the evidence supporting the use of EDTA chelation therapy is in the form of case reports and case series, published in peer review journals but lacking the numbers of patients we typically like to see. Many patients who have undergone chelation therapy have improvement in CAD symptoms such as chest pain. Chelation may also be able to lower plaque in the arteries as measured by EBCT heart scans, though this finding has not been published. In addition, there are approximately 12 published studies and 5 randomized controlled clinical trials regarding the use of EDTA chelation for CAD. Although each descriptive study did report a reduction in angina, they were uncontrolled clinical observations or retrospective data, typically with a small number of participants. Of the five clinical trials in which patients were randomly selected to receive chelation therapy or a placebo, three trials involved so few people that only a dramatic improvement could have been detected. The fourth
