Is There Creatine Balance in the Muscle?
Yes, the muscle has creatine equilibrium. Creatine has a normal turnover rate of 2 grams per day. That is, two grams of creatine are irreversibly degraded and, in its place, equivalent amount is synthesized to replace it. There is a balance between creatine pool inside the muscle cells and creatine circulating in the blood. After the start of creatine supplementation, this balance may be slightly perturbed, but the body quickly adjusts to the new equilibrium within a few days.
