Is There Conjunctiva-Associated Lymphoid Tissue in the Human?
Although the mucosal immune system is of increasing relevance, there is still little evidence for a respective tissue in the eye, especially in the human. Knop and Knop (p. 1270), in a study on a number of human autopsy tissues, provide evidence for the existence of a conjunctiva-associated lymphoid tissue (CALT) in normal individuals, its topographic anatomy, its continuation in the lacrimal drainage system, and its contribution to the secretory immune system. These findings characterize the basis for immunologic phenomena on the ocular surface and may enhance our understanding of physiologic homeostasis and pathologic alterations of the ocular surface. [Abstract] [Full Text] Extraocular Muscles Do More than Turn the Eye Extraocular muscles consist of two layers: orbital and global. Demer et al. (p. 1280) used magnetic resonance imaging in living people, and histological examination in cadavers, to demonstrate that only the global layer of each rectus extraocular muscle inserts on and