Is there any way for creatine to work in a non-responder?
The only factor that could make a difference that has been identified in the research is carbohydrate intake. When creatine is taken along with high amounts of carbohydrates, there is less variation in response. Many believe that there are certain products that will make non-responders into responders. This is very unlikely it is much more likely that these products just produce results related to the other ingredients. As noted above, the amount of creatine in muscle tissue simply cannot exceed a certain amount. Therefore, if one has initially high levels of creatine, they will not get a strong response from creatine supplementation no matter what. It is impossible to “supersaturate” muscle tissue with creatine. If one believes they are a non-responder and have tried taking creatine while carbohydrate loading, the best solution is to stop worrying about creatine and try other supplements.