Is there any permanent cure for thalassemia?
A successful bone marrow SCT enables normal life and growth. Gene therapy strategies are being tried but clinical use for routine benefit of patients is still far off. Problem is with the finding of optimum mode of delivery and persistent expression of the gene. However, recent studies on self-inactivating lentiviral vectors (SIN-LV) have given encouraging results and renewed hope in gene therapy(10,11).
