Is there any evidence that Clorpactin® causes scarring?
(Dr. Globus) No. It should not cause scarring at 0.2%. We know it causes slight irritation to the tissue of the bladder but not permanent harm. Clorpactin® will destroy a single cell if it can surround it entirely but solid tissue is not harmed with a 0.2% solution because those cells are in a group. Healthy bladder tissue (i.e. the bladder lining) should not be destroyed when the proper strength solution is used. The bladder is a sensitive area which requires the professional to monitor the pain threshold in individual patients and adjust the procedure both in terms of dosage and strength as needed. With the exception of a recent incident that came to our attention less than one year ago, where it was alleged that Clorpactin caused damage to a bladder that was in very bad shape prior to the instillation of Clorpactin, we have no knowledge of any cases of permanent damage to the bladder. This particular case involved over distention of the bladder which, along with the use of a 0.4% so
