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Is there any association between the use of the drug spinonolactone and tumors of the endocrine glands?

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Is there any association between the use of the drug spinonolactone and tumors of the endocrine glands?

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Spironolactone has an A ring similar to estrogen. Consequently, patients who take it can experience estrogen like side effects. These include breast enlargement, vaginal cytology changes etc. I am not aware of any incidence of adenomas on this drug.

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