Is there an increase in supra-gingival calculus associated with the use of MI Paste?
Casein Phosphopeptides (CPP) inhibits the transformation of amorphous calcium phosphate into crystalline phases (Holt and van Kemenade, 1989) such that they should not directly promote calculus formation but instead provide a plaque reservoir of soluble calcium phosphate ions capable of diffusing into subsurface enamel and promoting remineralization.