Is there an ideal approach for rapid-sequence induction in hypertensive patients?
Author(s): Alanoglu Z, Ates Y, Yilmaz AA, Tuzuner F Affiliation(s): Ankara University Medical Faculty, Department of Anesthesiology and Reanimation, 06100 Ankara, Turkey. zekeriyya_69@yahoo.com Publication date & source: 2006-02, J Clin Anesth., 18(1):34-40. Publication type: Randomized Controlled Trial STUDY OBJECTIVE: To compare 4 different anesthesia induction protocols, in a simulated model of rapid-sequence induction, in controlled hypertensive patients. DESIGN: Prospective, randomized, double-blind, clinical investigation. SETTING: Large metropolitan university hospital. PATIENTS: 120 ASA II-III adult hypertensive patients. INTERVENTIONS: Patients were allocated to 4 groups at random. After preoxygenation for 3 minutes, induction and tracheal intubation was performed in a 30 degrees head-up position. Thiopental (5-7 mg/kg) was the induction agent. Study groups were as follows: group LS (n = 30), lidocaine (1.5 mg/kg) and succinylcholine (1 mg/kg); group LR (n = 30), lidocaine (1.
