Is there an association between endometriosis and the risk of pre-eclampsia?
GROUND: An association between endometriosis and reduced risk of pre-eclampsia has recently been reported. Longitudinally-linked electronic hospital records are a valuable resource for investigating such findings in a large, population-based sample. Our aim was to determine whether women with a history of endometriosis were at modified risk for pregnancy hypertension or pre-eclampsia. METHODS: A population-based, longitudinal study of all women in the Australian state of New South Wales, aged from 15 to 45 years of age with a singleton birth during the period 2000–2005. Endometriosis was identified using ICD-10 codes. Endometriosis subgroups were analysed based on: (i) site of endometriosis (ovary or peritoneum), (ii) multiple (i.e. two or more) sites affected and (iii) infertility. To investigate the association between pregnancy hypertension and endometriosis, number of weeks gestation at birth and maternal age, we used logistic regression. RESULTS: In the 3239 (1.6%) women with endo
