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Is there an association between alopecia areata and Downs syndrome?

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Is there an association between alopecia areata and Downs syndrome?

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At least two series have found a higher (6 and 8.9%) than normal prevalence of alopecia areata in patients with Down’s syndrome. It is believed that this association is the result of patients with trisomy 21 being more suceptible to dysregulation of their immune system.

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