Is there a safe way of increasing the effect of chewed quid?
A. The effect of chewed quid can apparently be potentiated just by using mouthwash! Do not add the mouthwash to the leaves. Instead, just before putting the quid in your mouth, rinse your entire mouth out thoroughly (for at least 30 seconds) with a mouthwash that contains both menthol and alcohol. Cool Mint Listerine works well. This will noticeably increase the effect of chewed leaves. This effect makes pharmacological sense, as it is known that a mixture of alcohol, water, and menthol increases the permeability of mucous membranes to various drugs. Presumably it is increasing the rate of salvinorin absorption. It is possible that other ingredients in the mouthwash, such as eucalyptol may also be contributing to this effect. Another technique, which may be helpful, is to lightly brush the interior surfaces of the mouth with a toothbrush. This removes a layer of dead cells and consequently seems to improve absorption. If you will also be using the mouthwash technique, it is probably be
