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Is there a role for Aspirin in Venous Thromboembolism Prophylaxis Following Total Knee Replacement?

April 26, 2017aspirin knee PROPHYLAXIS replacement thromboembolism total venous

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Is there a role for Aspirin in Venous Thromboembolism Prophylaxis Following Total Knee Replacement?

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Podium No: 073 Wednesday, March 05, 2008 03:06 PM – 03:12 PM Location: Moscone Convention Center Room 3014-3018 Kevin John Bozic, MD, MBA San Francisco CA Andrew Auerbach, MD, MPH San Francisco CA Judy Maselli San Francisco CA Thomas Parker Vail, MD San Francisco CA Moderator(s): Henry D Clarke, MD Phoenix AZ Michael A Kelly, MD Hackensack NJ Results from this large secondary data analysis suggests that aspirin may be a safe and effective alternative to ACCP recommended agents for VTE prophylaxis in carefully selected TKR patients. American College of Chest Physicians (ACCP) guidelines for venous thrombo-embolism prophylaxis (VTEP) following total knee replacement (TKR) favor LMWH, pentasaccharides (Fondaparinux), and warfarin over aspirin. However, recent data suggest that ACCP recommended therapies may increase bleeding complications following TKR. To determine the risks and benefits of various VTEP strategies, we compared rates of DVT, PE, surgical site bleeding, and mortality in a