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Is there a risk of ovarian cancer associated with postmenopausal hormone use?

April 26, 2017associated cancer Hormone ovarian postmenopausal risk

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Is there a risk of ovarian cancer associated with postmenopausal hormone use?

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The results of studies on ovarian cancer and hormone use are inconsistent. Some studies have found a slight increase in risk of ovarian cancer among women using estrogen therapy. Other studies, however, have found no association between hormone use and ovarian cancer risk (104, 105). Because most studies have followed women using estrogen alone, there is currently not enough data to assess the potential effects of combined therapy on ovarian cancer (105). One recent study suggested that combined estrogen-progestin regimens do not increase the risk of ovarian cancer if progestin is used for more than 15 days per month (96). Although it appears that estrogen may increase the risk of ovarian cancer, the increased risk appears to be limited to women who have used estrogens for 10 years or more (97). The results of further analyses are expected to be published soon.