Is there a possible association between the steroid injections and menstrual bleeding?
“I have received 3 sessions of injections. The derm did not say what they were exactly except that the first 2 were 2-3 mg and after the second did nothing he increased it to 10. I had no side effects the first 2 times. Since the third time, about 6 weeks ago, I have experienced menstrual bleeding with only a weeks break between each week of bleeding. The last time lasted over 10 days and I am now on low dose estrogen which has stopped it. Is there a possible association between the steroid injections and menstrual bleeding?” For some people the corticostroid injections themselves can be quite painful and may promote a stress type of reponse. Steroids comprise part of the stress cascade and could have promoted the same if absorbed systemically after the dermal injections. Stress per se is related to menstrual irregularities which may result from the combined effects of steroids on the levels of luteinizing hormone (which controls ovulation), estrogen, progesterone, and even androgens.