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Is there a link between the food-cobalamin malabsorption and the pernicious anemia?

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Is there a link between the food-cobalamin malabsorption and the pernicious anemia?

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Andrs E; Noel E; Henoun Loukili N; Coca C; Vinzio S; Blickl JF Service de médecine interne, hôpitaux universitaires de Strasbourg, 1 porte de l’Hôpital, 67091 Strasbourg Cedex, France. emmanuel.andres@chru-strasbourg.fr BACKGROUND: A relation between food-cobalamin malabsorption and pernicious anemia has been suggested, particularly in the event of food-cobalamin malabsorption related to hypochlorhydric atrophic gastritis. STUDY DESIGN: This work describes three cases of well-documented cobalamin deficiency related to food-cobalamin malabsorption in three women aged 56, 82 and 68 Years who had atrophic gastritis (not associated with Helicobacter pylori infection) and later developed authentic pernicious anemia. CONCLUSIONS: This work illustrates the potential relation between these two disorders responsible for cobalamin deficiency.

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