IS THERE A LINK BETWEEN OVARIAN CANCER AND HORMONE REPLACEMENT THERAPY?
Yes. A recent study following over 44,000 postmenopausal women during a 20-year span concluded that estrogen use increases the risk of ovarian cancer. In this study, women who used estrogen alone for 10-19 years were twice as likely to develop ovarian cancer than women who did not use postmenopausal hormones. For women who used estrogen for 20 or more years, the risk of ovarian cancer increased to three times that of women who did not use postmenopausal hormones. Because most studies have followed women using estrogen alone, there are currently not enough data to assess the potential effects of the estrogen-progestin combination on ovarian cancer. More data is needed to determine the estrogen-progestin risk for ovarian cancer.