Is there a difference between unilamellar and multilamellar liposomes?
Cosmetic liposomes always consist of a mixture of unilamellar and multilamellar liposomes as the manufacturing process for pure unilamellar liposomes is much more elaborate and hence more expensive. In contrast to what can be seen in the advertising and media fields, the number of shells has no influence on the encapsulation, penetration and efficacy of active agents. The concentration of phosphatidylcholine (PC) is the crucial factor in the efficacy of liposomes. Unfortunately, PC has no specific denomination in the INCI but is listed as lecithin.
