Is there a causal relationship between TM and seizures – any relationship?
By definition, TM normally affects only the spinal cord. Seizures are caused by abnormal discharges in the brain. Therefore, TM should not be a cause of seizures. However, there are processes of inflammation that may affect both the brain and the spinal cord at the same time. In those cases, the TM would be caused by inflammation of the spinal cord and the seizures by inflammation or injury to the cerebrum (part of the brain). Reference: Randall T. Schapiro, MD. Symptom Management in Multiple Sclerosis. New York: Demos Medical Publishing Co., Inc., 1998.