Is the UC Irvine Comprehensive Brain Tumor Program involved in basic science brain tumor research?
A. The UC Irvine Comprehensive Brain Tumor Program is actively involved in both translational basic science brain tumor research as well as molecular biology brain tumor research. Translational efforts include those led by Dr. Daniela Bota in the Chao Family Comprehensive Cancer translational research laboratory and Dr. Mark Linskey and the Beckman Laser Institute studying applications of modulated imaging to investigate brain tumor imaging and intraoperative mapping. Molecular biology efforts include those lead by Dr. Yi-Hong Zhou at the Brain Tumor Research Laboratory. Dr. Zhou is studying the PAX6 tumor suppressor pathway. In addition, Drs. Zhou and Linskey are exploring the differential biology of tumor stem cells versus the main tumor cell population and the molecular modeling of brain tumor patient prognosis.