Is the Therapeutic Potential of Stem Cells for Myocardial Regeneration Limited by Proarrhythmic Effects?
Pp. 283-295 Oliver Wolfram, Matthias Hammwöhner and Andreas Goette [Abstract] [Purchase Issue/Articles] Angiotensin Receptor Blockers in Chronic Heart Failure: Clinical Implications and Molecular Mechanisms Pp. 296-303 Hadyanto Lim and Zhu Yi Zhun [Abstract] [Purchase Issue/Articles] Abstracts [Back to top] [Purchase Issue/Articles] Etiology of the Metabolic Syndrome Amy Z. Fan The metabolic syndrome (MSynd) refers to a clustering of cardiovascular risk factors characterized by obesity, impaired glucose tolerance/type 2 diabetes, atherogenic dyslipidemia, and hypertension. The tendency that multiple risk factors were often present in the same individual prompted researchers to search for the underlying pathophysiology of the MSynd. In an inventory of hypotheses on causative mechanisms for the MSynd, plausible mechanisms include insulin re-sistance, leptin resistance, visceral obesity, beta-cell dysfunction, endothelial dysfunction, neuroendocrine origin (sympathetic overactivity and va
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- Is the Therapeutic Potential of Stem Cells for Myocardial Regeneration Limited by Proarrhythmic Effects?