Is the risk assessment adjusted for IVF pregnancies?
The literature consensus is that biochemistry results differ slightly in IVF pregnancies when compared to non-IVF pregnancies leading to relatively higher screen positive rates in IVF pregnancies. In order to prevent this effect, IVF specific adjustment factors are applied to biochemistry results from IVF pregnancies prior to their use in determining the Down syndrome risk.
The literature consensus is that biochemistry results differ slightly in IVF pregnancies when compared to non-IVF pregnancies leading to relatively higher screen positive rates in IVF pregnancies. In order to prevent this effect, IVF specific adjustment factors are applied to biochemistry results from IVF pregnancies to determine the Down syndrome risk.