Is the rhesus monkey (Macaca mulatta) comparable to humans?
Ganzer R; Khler D; Neuhaus J; Dorschner W; Stolzenburg JU Department of Urology, University of Leipzig, Liebigstrasse 20, 04103 Leipzig, Germany. roman.ganzer@gmx.de The physiology of the muscle systems of the human lower urinary tract is still not known in detail. To study the functional basics of this complex organ system, experiments are often performed in animal models including rhesus monkeys. To apply the results of animal model studies to the humans, a clear knowledge of the comparative anatomy of both species is necessary. However, detailed comparative studies of the lower urinary tract of the rhesus monkey and the humans are lacking. Accordingly, a detailed study on the sphincteric musculature of the lower urinary tract of the rhesus monkey was performed in order to demonstrate anatomical correspondences and differences between both species. The lower urinary tract anatomy was investigated in 18 male and female rhesus monkeys (Macaca mulatta) by serial sections. Immunohistoche
