Is the relationship of high triglyceride and/or low HDL levels with coronary heart disease causal?
• Will reduction of high triglyceride and/or elevation of HDL cholesterol help prevent coronary heart disease? • Under what circumstances should triglycerides and HDL be measured? • What can be accomplished by dietary, drug, and other hygienic treatments? • Under what circumstances should active intervention to lower triglyceride and/or raise HDL cholesterol be considered in high-risk individuals and the general population? • What are the significant questions for continuing research? To address these questions, the National Heart, Lung, and Blood Institute and the Office of Medical Applications of Research of the National Institutes of Health convened a Consensus Development Conference on Triglyceride, High Density Lipoprotein, and Coronary Heart Disease on February 26-28, 1992. After 2 days of presentations by experts and discussion by the audience, a consensus panel drawn from specialists and generalists from the medical profession and related scientific disciplines, clinical invest