Is the relationship between blood cholesterol levels and coronary heart disease causal?
• Will reduction of blood cholesterol levels help prevent coronary heart disease? • Under what circumstances and at what level of blood cholesterol should dietary or drug treatment be started? • Should an attempt be made to reduce the blood cholesterol levels of the general population? • What research directions should be pursued on the relationship between blood cholesterol and coronary heart disease? Panel’s Conclusions Elevated blood cholesterol level is a major cause of coronary artery disease. It has been established beyond a reasonable doubt that lowering definitely elevated blood cholesterol levels (specifically blood levels of low-density lipoprotein cholesterol) will reduce the risk of heart attacks due to coronary heart disease. This has been demonstrated most conclusively in men with elevated blood cholesterol levels, but much evidence justifies the conclusion that similar protection will be afforded in women with elevated levels. After careful review of genetic, experimenta
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- What research directions should be pursued on the relationship between blood cholesterol and coronary heart disease?
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- Is the relationship between blood cholesterol levels and coronary heart disease causal?
