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Is the Nnt deletion required for a robust DIO response?

deletion dio nnt Response robust
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Is the Nnt deletion required for a robust DIO response?

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No. B6/J males do respond more robustly to DIO; however, B6/NJ mice develop DIO, and NON/ShiLtJ (also with a wild-type Nnt) males are even more DIO-responsive. View a DIO strain comparison article.

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