Is the NCI supporting research that quantifies the effects of biospecimen handling variables on biospecimen quality?
The NCI Office of Biorepositories and Biospecimen Research (OBBR) has established the Biospecimen Research Network (BRN) to systematically address the impact of specific variables in individual specimen types on molecular data from given analysis platforms. The goal of the BRN is to address these issues by sponsoring, conducting, and collaborating on studies to assess the effects of human specimen preanalytical variables on the outcome of genomic and proteomic studies conducted for clinical diagnosis and cancer research purposes. To this end, the Intramural BRN Laboratory is conducting a series of research projects in collaboration with intramural and extramural collaborators. The recently launched extramural research program, “Biospecimen Research for Molecular Medicine,” is designed to systematically define the impact of key preanalytical variables in human biospecimens of specific type on downstream molecular data generated from specific molecular analysis platforms and to develop i
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