Is the lack of oxalate degrading bacteria a risk factor for calcium oxalate urolith formation in cats?
Jody P. Lulich; University of Minnesota. $19,840 Calcium oxalate (CaOx) is the most common urinary stone in cats. Urinary stones are associated with difficulty urinating, blood in the urine, and life-threatening urinary tract obstruction. Stone removal is the treatment of choice; however, many will recur. Excessive urine oxalate concentration predisposes cats to CaOX urinary stones. Bacteria that degrade oxalate in the intestinal tract are correlated with absence of oxalate stones in other species. This study is designed to determine the association of these bacteria with development of urinary stones in cats. The researchers predict that the prevalence of intestinal bacterial that degrade oxalate will be lower in cats with CaOx than in clinically healthy cats. These results will help in the development of new therapies, such as probiotics, to manage CaOx urinary stones in cats. MT08-009: Unraveling feline stone genetics: Searching for associations between polymorphisms in candidate ge
Jody P. Lulich; University of Minnesota. $19,840 Calcium oxalate (CaOx) is the most common urinary stone in cats. Urinary stones are associated with difficulty urinating, blood in the urine, and life-threatening urinary tract obstruction. Stone removal is the treatment of choice; however, many will recur. Excessive urine oxalate concentration predisposes cats to CaOX urinary stones. Bacteria that degrade oxalate in the intestinal tract are correlated with absence of oxalate stones in other species. This study is designed to determine the association of these bacteria with development of urinary stones in cats. The researchers predict that the prevalence of intestinal bacterial that degrade oxalate will be lower in cats with CaOx than in clinically healthy cats. These results will help in the development of new therapies, such as probiotics, to manage CaOx urinary stones in cats. MT08-009: Unraveling feline stone genetics: Searching for associations between polymorphisms in candidate ge
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