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Is the incidence of perimyocarditis increased following Campylobacter jejuni infection?

April 26, 2017campylobacter center increased infection jejuni National PubMed

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Is the incidence of perimyocarditis increased following Campylobacter jejuni infection?

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Preliminary case reports have suggested an association between Campylobacter jejuni infection and occurrence of perimyocarditis. In the present study we analysed the incidence of perimyocarditis requiring hospitalization in a Danish cohort of 6,204 patients with Campylobacter-positive stool cultures and compared it to the incidence in a matched control cohort comprising 62,040 subjects. We found no cases of pericarditis in the Campylobacter population and an incidence rate of 3.2 [95% confidence interval (CI): 0.8-12.9] per 100,000 person-years in the control population. The incidence rate of myocarditis was 16.1 (95% CI: 2.3-114.4) per 100,000 person-years in the Campylobacter population compared to 1.6 (95% CI: 0.2-11.4) per 100,000 person-years in the control cohort. We found no statistically significant difference in perimyocarditis between the two groups.