Is the efficacy of assisted reproductive technology to prevent male-to-female HIV transmission evidence-based?
As noted previously, one can estimate that 4000 cycles have performed worldwide in assisted reproduction clinics using the combination of gradient separation followed by HIV undetectable level within the final semen preparation before the use of assisted reproductive techniques, without any reported contamination. One has to consider that the two known cases of contamination through IUI should not be regarded as method failures: the contamination that occurred in the USA and reported by the CDC at the beginning of the 1990s (Anonymous, 1990) used a method of sperm centrifugation followed by insemination of the cell pellet, i.e. sperm and round cells. It thus demonstrated that leukocytes and macrophages known to be present in any normal semen are able to transmit the disease, which after all is not really a surprise. The second but unpublished case that recently occurred in Japan (anonymous personal communication) illustrated two procedure risks: the treated sperm came from a patient wi
Related Questions
- should the option of embryo gender selection be available to infertile couples undergoing assisted reproductive technology?
- Is the efficacy of assisted reproductive technology to prevent male-to-female HIV transmission evidence-based?
- Do monochorionic dizygotic twins increase after pregnancy by assisted reproductive technology?
