Is the default radiological or neurological orientation?
(John Ashburner) Neurological and radiological conventions only relate to visualization of axial images. They are unrelated to how the data are stored on disk, or even how the real-world coordinates are represented. It is more appropriate to consider whether the real-world coordinate system is left- or right-handed (see below). Talairach and Tournoux use a right-handed system, whereas the storage convention of ANALYZE files is usually considered as left-handed. These coordinate systems are mirror images of each other (if you are a psychologist, try explaining why mirror images appear to be left-right flipped, rather than flipped up-down, or back-front). Transforming between left- and right-handed coordinate systems involves flipping, and can not be done by rotations alone.
