Important Notice: Our web hosting provider recently started charging us for additional visits, which was unexpected. In response, we're seeking donations. Depending on the situation, we may explore different monetization options for our Community and Expert Contributors. It's crucial to provide more returns for their expertise and offer more Expert Validated Answers or AI Validated Answers. Learn more about our hosting issue here.

Is the Arg-Gly-Asp sequence the site for foot-and-mouth disease virus binding with cell receptor?

April 26, 2017arg-gly-asp Binding CELL disease foot-and-mouth PubMed receptor sequence site virus

0

Posted

Is the Arg-Gly-Asp sequence the site for foot-and-mouth disease virus binding with cell receptor?

1 Answer

0

Posted

The Arg-Gly-Asp sequence is being found in an increasing wide range of proteins with “adhesive” function. Studying a series of synthetic peptide fragments of VP1 protein of FMDV, we showed that peptides containing the Arg-Gly-Asp sequence, but not control peptides, inhibited FMDV binding to pig kidney cells in vitro, thus indicating participation of that sequence in FMDV binding to host cells.