Is submucosal epinephrine injection necessary before polypectomy?
Author(s): Hsieh YH, Lin HJ, Tseng GY, Perng CL, Li AF, Chang FY, Lee SD Affiliation(s): Buddhish Tzu Chi Dalin General Hospital, Taiwan, ROC. Publication date & source: 2001-09, Hepatogastroenterology., 48(41):1379-82. Publication type: Clinical Trial; Randomized Controlled Trial BACKGROUND/AIMS: Polyps of the gastrointestinal tract are usually removed due to their link to bleeding, obstruction and malignancy. However, complications may occur following polypectomy. The aim of this study was to assess whether submucosal epinephrine injection before polypectomy could reduce the incidence of bleeding and perforation. METHODOLOGY: Between June 1997 and November 1999, patients with sessile polyps of the gastrointestinal tract found in our endoscopic unit were randomized to receive submucosal epinephrine injection (epinephrine group) or no injection (control group) before polypectomy. In the epinephrine group, epinephrine (1:10,000) was injected surrounding the stalk of the polyp until the