Is subcellular fractionation and differential centrifugation the same?
No, they are not the same, but one is used to the other. So, in order to conduct a subcellular fractionation, one uses differential centrifugation as a too, or technique. Subcellular fractionation is where you separate the different parts of a tissue sample, e.g. the brain, or the heart, or some other organ, into the cellular components, like nuclei, mitochondria, microsomes, etc. In order to accomplish this, one usually uses the method of differential centrifugation, where you grind up the tissue, then centrifuge it at different speeds and different g-forces. So, the basic answer to the question is NO, they are different.
