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Is serodiagnosis of herpes simplex encephalitis safe?

April 26, 2017encephalitis Herpes safe serodiagnosis simplex

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Is serodiagnosis of herpes simplex encephalitis safe?

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We present a case of probable tuberculous meningitis in which serological changes ‘diagnostic’ of herpes simplex encephalitis were found. Evidence is provided that the serological changes in this case represent a true false positive, and that reliance on clinical plus serological criteria to diagnose herpes simplex encephalitis could result in failure to diagnose and treat tuberculous meningitis.