Is routine sampling of fetal fibronectin justified?
KEY POINTS Spontaneous preterm birth is associated with elevated cervicovaginal fetal fibronectin levels, especially in women who deliver at an early gestational age. A recent study suggests that antibiotic therapy in women with a positive fetal fibronectin screening test does not reduce the incidence of spontaneous preterm birth or improve neonatal outcomes. Fetal fibronectin cannot be recommended as a screening test for preterm birth.