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Is room air better than 100% oxygen for the resuscitation of the depressed full-term newborn?

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Is room air better than 100% oxygen for the resuscitation of the depressed full-term newborn?

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Recently, I was called for resuscitation of a newborn infant with bradycardia and no respiratory effort at birth. The hospital has a practice (currently under review) of using 100% oxygen for newborn resuscitation. As a paediatric trainee, having trained in various regions of the UK, I have noticed that units vary in their choice between use of room air and the more conventional 100% oxygen for neonatal resuscitation. What is the evidence behind using room air versus 100% oxygen in resuscitation of the depressed newborn?

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