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Is Psilocybin metabolized into Psilocyin or vise versa?

April 26, 2017metabolized psilocybin versa vise

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Is Psilocybin metabolized into Psilocyin or vise versa?

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Psilocin is the pharmacologically active agent in the body after ingestion of psilocybin or psychedelic mushrooms. Psilocybin is rapidly dephosphorylated in the body to psilocin which acts as a 5HT2A, 5HT2C and 5HT1A agonist. It’s effects are thought to come from it’s ability to mimic serotonin (5-HT) and thereby activate serotonin receptors in the brain. Psilocin has no significant effect on dopamine receptors (unlike LSD) and only affects the norephenephrine system at very high dosages.