Important Notice: Our web hosting provider recently started charging us for additional visits, which was unexpected. In response, we're seeking donations. Depending on the situation, we may explore different monetization options for our Community and Expert Contributors. It's crucial to provide more returns for their expertise and offer more Expert Validated Answers or AI Validated Answers. Learn more about our hosting issue here.

Is primitive neuroectodermal tumour (PNET) different to Ewings sarcoma ?

April 26, 2017different ewing neuroectodermal PNET Primitive sarcoma Tumour

0

Posted

Is primitive neuroectodermal tumour (PNET) different to Ewings sarcoma ?

1 Answer

0

Posted

Peripheral primitive neuroectodermal tumours (PNET, or more correctly pPNET) start in bone or soft tissues. Like Ewing’s sarcoma (ES) they are composed of small-blue-round cells. They differ from ES in that they show more developed features of cells associated with the nervous system. Genetic analyses show that both pPNET and ES share a unique genetic alteration, an exchange of material between chromosomes 11 and 22. Also, ES and pPNET have a similar response to chemotherapy.