Is prescription Prilosec® the same as Prilosec OTC?
Prilosec and Prilosec OTC are different in indication and dose form. Prilosec OTC is indicated for the treatment of frequent heartburn (heartburn that occurs two or more days per week). Prilosec is a prescription medication indicated for the treatment of many other acid-related conditions. However, the omeprazole active ingredient in Prilosec became available over the counter in 2003 in the form of Prilosec OTC.