Is Parkinsons Disease An Autosomal Dominant Trait Or Autosomal Recessive Trait?
There are a number of different autosomal dominant and recessive forms of Parkinson disease. They are called PARK1, PARK2, and so on: * PARK1 is an autosomal dominant trait and is due to mutation in the alpha-synuclein gene (SNCA) on chromosome 4q21; * PARK2 is an autosomal recessive trait and is due to mutation in the gene encoding parkin on chromosome 6q25.2-q27; * PARK3 is an autosomal dominant trait and is due to a gene on chromosome 2p13; * PARK4 is an autosomal dominant trait and is due to a gene on chromosome 4p15; * PARK5 is an autosomal dominant trait and is due to mutation in the UCHL1 gene on chromosome 4p14; * PARK6 is an autosomal recessive trait and is due to mutation in a gene on chromosome 1p distinct from DJ1; * PARK7 is an autosomal recessive trait and is due to mutation in the DJ1 gene on 1p36; * PARK8 is an autosomal dominant trait and is due to a gene on chromosome 12p11.2-q13.1; * PARK9 is an autosomal recessive trait and is due to a gene on chromosome 1p36; * PAR