Is nitrous oxide safe to use as an analgesic?
A. Laughing gas diluted with oxygen creates what we call “happy gas.” More percentage oxygen is available during the procedure than from room air. Nitrous oxide seems to act as a mild reversible nerve poison. Considered the safest of the anesthetic gases, nitrous oxide is a pleasant distraction for most, creating skin and gum numbness, often making the dental shot unnecessary or painless if needed. At least two B vitamins are oxidized by nitrous oxide, folic acid and vitamin B12. After a nitrous oxide experience, we recommend replenishing both vitamins with a tasty sublingual form. Very strong clinical effect of the happy gas is felt if the patient is anemic, even from very low doses of nitrous oxide.