Is nefazodone toxic if an overdose is taken?
Seven overdoses of nefazodone have been reported. The highest reported overdose was 11,200 mg. In some cases nefazodone was taken along with alcohol and/or other medications. All seven people who took an overdose recovered. • What precautions are necessary when switching between nefazodone and an MAO inhibitor? When switching from an MAO inhibitor to nefazodone, there should be a 14-day interval between the discontinuation of the MAOI and the initiation of nefazodone therapy. When switching from nefazodone to an MAOI, a 7-day interval is adequate, because of nefazodone’s short half-life. • What does nefazodone cost? Nefazodone is supplied in tablets ranging from 100 mg to 250 mg in strength. The 100 mg tablets cost pharmacies nearly as much as the 250 mg tablets. It is expected that all strengths of nefazodone will be sold for between $0.80 and $1.25 per tablet. • Might nefazodone be effective when a person has not responded to other antidepressants? Although there is no data on this,
