Is naltrexone like Antabuse® (disulfiram)?
Unlike Antabuse® (disulfiram), naltrexone does not produce an adverse effect in combination with alcohol. Naltrexone in and of itself is a passive substance with no stimulating or tranquilizing effects. Most patients do not notice any effect of naltrexone, other than observing that their thoughts and behaviors move them to drink less or abstain.